Fig. 4. Inhibition of XOR by allopurinol partially inhibits RONS production triggered by both7-KC and TRIOL. DCF-DA associated cell fluorescence measured after a 2 h incubation of RBCs with TRIOL or 7-KC preceded by 1 h pre-treatment in the absence or in the presence of allopurinol (500 µM). Imagine representative of three separate experiments carried out in duplicate with comparable results.